Girish Mahajan (Editor)

(R) 3 amino 2 methylpropionate—pyruvate transaminase

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EC number
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  37279-00-8
KEGG  KEGG entry

In enzymology, a (R)-3-amino-2-methylpropionate—pyruvate transaminase (EC is an enzyme that catalyzes the chemical reaction

(R)-3-amino-2-methylpropanoate + pyruvate 2-methyl-3-oxopropanoate + L-alanine

Thus, the two substrates of this enzyme are (R)-3-amino-2-methylpropanoate and pyruvate, whereas its two products are 2-methyl-3-oxopropanoate and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is (R)-3-amino-2-methylpropanoate:pyruvate aminotransferase. Other names in common use include D-3-aminoisobutyrate-pyruvate transaminase, beta-aminoisobutyrate-pyruvate aminotransferase, D-3-aminoisobutyrate-pyruvate aminotransferase, D-3-aminoisobutyrate-pyruvate transaminase, (R)-3-amino-2-methylpropionate transaminase, and D-beta-aminoisobutyrate:pyruvate aminotransferase. But some additional information is that this enzyme catalyzed it transamination with L isomer, but D isomer in natural form, inactive as substrate. Also other names of enzymes similar to this contains, L-3-aminoisobutyrate transaminase, beta-aminobutyric transaminase, L-3-aminoisobutyric aminotransferase, and beta-aminoisobutyrate-alpha-ketoglutarate transaminase.


(R)-3-amino-2-methylpropionate—pyruvate transaminase Wikipedia