|EC number 18.104.22.168|
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|CAS number 9027-92-3|
BRENDA BRENDA entry
KEGG KEGG entry
In enzymology, a (R)-2-methylmalate dehydratase (EC 22.214.171.124) is an enzyme that catalyzes the chemical reaction(R)-2-methylmalate
Hence, this enzyme has one substrate, (R)-2-methylmalate, and two products, 2-methylmaleate and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (R)-2-methylmalate hydro-lyase (2-methylmaleate-forming). Other names in common use include citraconate hydratase, citraconase, citramalate hydro-lyase, (−)-citramalate hydro-lyase, and (R)-2-methylmalate hydro-lyase. This enzyme participates in valine, leucine and isoleucine biosynthesis and c5-branched dibasic acid metabolism. It employs one cofactor, iron.