Puneet Varma (Editor)

(KDO) lipid IVA 3 deoxy D manno octulosonic acid transferase

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EC number
  
2.4.99.13

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

(KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.13, KDO transferase, waaA (gene), kdtA (gene), Kdo transferase, 3-deoxy-D-manno-oct-2-ulosonic acid transferase, 3-deoxy-manno-octulosonic acid transferase) is an enzyme with systematic name CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase. This enzyme catalyses the following chemical reaction

alpha-Kdo-(2->6)-lipid IVA + CMP-alpha-Kdo ⇌ alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP

The bifunctional enzyme from Escherichia coli transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA.

References

(KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase Wikipedia
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