Trisha Shetty (Editor)

(3S,4R) 3,4 dihydroxycyclohexa 1,5 diene 1,4 dicarboxylate dehydrogenase

Updated on
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  162032-77-1
KEGG  KEGG entry

In enzymology, a (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase (EC is an enzyme that catalyzes the chemical reaction

(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+ 3,4-dihydroxybenzoate + CO2 + NADH

Thus, the two substrates of this enzyme are (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate and NAD+, whereas its 3 products are 3,4-dihydroxybenzoate, CO2, and NADH.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase. Another name in common use is (1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase. This enzyme employs one cofactor, iron.


(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase Wikipedia