|Aliases EPB42, PA, SPH5, erythrocyte membrane protein band 4.2|
External IDs OMIM: 177070 MGI: 95402 HomoloGene: 93 GeneCards: EPB42
Erythrocyte membrane protein band 4.2 is a protein that in humans is encoded by the EPB42 gene.
Protein 4.2 is a cytoskeleton protein found in red blood cells.
Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of protein 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property regulation. Mutations in the EPB42 gene are associated with recessive spherocytic elliptocytosis and recessively transmitted hereditary hemolytic anemia.